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Ældre eller bevidsthedspåvirkede patienter Nedsat lungefunktion Forhøjet intrakranielt tryk Hypotension i forbindelse med hypovolæmi Prostatahypertrofi Hypotyroidisme Pancreatitis Bør undgås ved svær overfølsomhedsreaktion på andre opioider. Egentlig allergi er Puppy yderst sjælden. Dosis kan evt. stige efter behov. Ældre. Dosis bør ne